Madalyn Fritch

Biography

Education

Pursuing a B.S. in Bioengineering with a minor in Mechanical Engineering at the Swanson School of Engineering, University of Pittsburgh.

Research

I am working with Dr. Hang Lin to research photocrosslinkable materials for tissue regeneration, human bone marrow stem cell applications in scaffold activation, live cell-scaffold fabrication using visible light-based projection stereolithography, and in vitro engineering of osteochondral tissue. My projects focus on improving therapeutic treatments for osteoarthritic (OA) cartilage caused by repeated degradation and inflammation. Currently, I am researching the effect of soluble, cartilage extracellular matrix on chondrocyte and human mesenchymal stem cell-derived engineered cartilage in an inflammatory articular cartilage model via 3D hydrogel scaffolds. My results will be used to better understand the mechanism and methodology of inflammation modulation for diseased cartilage in the joint space to promote regeneration and mitigate the degeneration of OA cartilage.

Mentor

Hang Lin

Awards

  • Swanson School of Engineering Summer Research Fellowship 2017
  • OCC Pitt Advantage Grant 2015
  • University of Pittsburgh Medical School, Summer Undergraduate Research Program 2014